All you need to know about Cryogenic Preservation

 

All you need to know about Cryogenic Preservation

Overview

In science, two procedures, namely Vitrification and Slow cooling, are practiced to preserve the biological materials such as cells, bone marrow, DNA, etc. at the low temperature, compared to their normal temperatures.

Cryobiology:

The study of life below very low temperature is known as cryobiology. The advantages of cryobiology are:

·         Helps preserve the biological materials

·         By this, the biological materials such as cells, gametes, embryos, bone marrow, DNA, etc. can be preserved for a longer time.

·         It helps to examine the adapting nature of animals under low temperatures.




Cryopreservation:

It is the process that comes under the Cryobiology in which the cell is kept under the extremely low temperature, which causes the cell to prevent its biological, chemical reactions. Eventually, the cell leads to death. At times, the cell that is kept under cryopreservation may get damaged when it is exerted to the low temperature. Some of the biological materials are kept under low temperature, which is the liquid nitrogen liquid phase. Since cryogenic preservation is the best preservation process, some complex biological compounds stop their biological, chemical reactions. To be released from the risk, the two techniques mostly applied are Slow Cooling and Vitrification.

Cryopreservation of embryos advantages and disadvantages in animals are many, but here we will focus on the benefits of process of cryopreservation. The top advantages of Cryoprotectants are:

·         Assists the material from the rapid cooling

·         Prevents the development of ice in the intracellular region

·         When the cell undergoes a high concentration of solute, it prevents dehydration.

·         Accommodates the cell for functioning after the rewarming

Difference between Controlled Slow Cooling and Vitrification in Cryopreservation of Biological Materials

1.       The Vitrification technique is simple, whereas the slow cooling technique is a complex one.

2.       The Vitrification technique is safer, and Controlled Slow Cooling is a risky technique.

3.       The Vitrification technique is costly, and in contrast to that, Controlled Slow Cooling is cheaper.

4.       The Vitrification technique is the most successful compared to the Controlled Slow Cooling technique.

Conclusion

Cryptogenic preservation is considered in the world of science to preserve biological materials such as cells, sperms, gametes, embryos, bone marrow, DNA, etc. for a longer time.

Location: Canton, TX 75103, USA

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